Clayton Weishuhn – New England Patriots
Weishuhn had a two year career in the NFL, and he still holds the Patriots’ single-season record for tackles with 229 in 1983. His 229-tackle campaign was in his second season, but it was the last full season he’d play. He suffered a knee injury in Week 1 of the 1984 season which cost Weishuhn his third year. The knee problems persisted and he ended up missing the 1985 season as well. After suffering also groin and hamstring injuries, this limited him to just 4 games in the 1986 season, which was his last in the league.
Alvin Williams – Toronto Raptors
From 1997 until 2007, Williams was a pretty great point guard for the Raptors. However he missed a third of the 2003-04 and the entire 2004-05 season with a serious knee injury, Williams did eventually join the lineup again at the start of the 2005-06 season. Sadly, the injured knee found him back on the injured list after playing just one game that season. He is officially retired now.